Production of Tl Antibody by Mice Immunized with Tl- Cell Populations

نویسندگان

  • Katsutoshi Komuro
  • Edward A. Boyse
  • Lloyd J. Old
چکیده

TL(-) mice make TL antibody when immunized with spleen or bone marrow cells from TL(+) donors, despite the fact that these cells do not express TL antigen. This has been shown to depend on maturation of TL(-) precursors, contained in the inoculum, into TL(+) cells under influence of the recipient's thymus; the differentiated TL(+) cells then evoke production of TL antibody.

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عنوان ژورنال:
  • The Journal of Experimental Medicine

دوره 137  شماره 

صفحات  -

تاریخ انتشار 1973